CTCF binding landscape in jawless fish with reference to Hox cluster evolution
Abstract The nuclear ORG COCONUT FLAKES protein CCCTC-binding factor (CTCF) contributes as an insulator to chromatin organization in animal genomes.Currently, our knowledge of its binding property is confined mainly to mammals.In this study, we identified CTCF homologs in extant jawless fishes and performed ChIP-seq for the CTCF protein in the Arct